Paxillin anticorps (AA 29-33)
Aperçu rapide pour Paxillin anticorps (AA 29-33) (ABIN5689331)
Antigène
Voir toutes Paxillin (PXN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 29-33
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Specificité
- This antibody detects endogenous level of total Paxillin protein.
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Purification
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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Immunogène
- Paxillin (Ab-31) antibody was raised against a peptide sequence around aa.29~33 (T-P-Y-S-Y) derived from Human Paxillin.
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Indications d'application
- Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store antibody at -20°C for up to one year.
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- Paxillin (PXN)
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Autre désignation
- Paxillin
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Sujet
- An antiphosphotyrosine antibody was used to identify proteins that are phosphorylated in Rous sarcoma virus-transformed chick embryo fibroblasts, and a 76-kD protein was obtained that localizes to focal adhesions at the ends of actin-containing stress fibers in nontransformed cells (Ref.1). This protein was purified from chicken gizzard smooth muscle, and was named Pxn (Paxillin) ('paxillus' means 'small stake' or 'peg' in Latin) as a protein tethered to the membrane at focal adhesions
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Poids moléculaire
- 68 kDa
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ID gène
- 5829
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NCBI Accession
- NP_001074324
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UniProt
- P49023
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Pathways
- Signalisation MAPK, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
Antigène
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